Barack Obama has seen a lot of difficult moments in his time as the former US President, but nothing could have prepared him for the feelings he would experience upon learning of his daughter Sasha’s devastating medical diagnosis at birth.

The politician and his spouse, Michelle, are pleased to be the parents of two grown, content, and healthy children, Malia, 25, and Sasha, 22.

People ask me what was the hardest time in my life — they ask, well what about during the debt ceiling debate and this and that and the other thing.” Barack disclosed the diagnosis while out on the 2012 campaign trail.